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Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer
BACKGROUND: 5-Fluorouracil (5-FU) is the cornerstone of chemotherapeutic treatment for patients with colorectal cancer. The enzyme thymidine phosphorylase (TP) catalyzes the conversion of 5-FU to its active metabolite, 5-fluoro-2’-deoxyuridine. TP is expressed in tumour epithelial cells and stromal...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058433/ https://ncbi.nlm.nih.gov/pubmed/24936150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6890-14-25 |
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