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High-Resolution Analysis of DNA Copy Number Using Oligonucleotide Microarrays

Genomic copy number alterations are a feature of many human diseases including cancer. We have evaluated the effectiveness of an oligonucleotide array, originally designed to detect single-nucleotide polymorphisms, to assess DNA copy number. We first showed that fluorescent signal from the oligonucl...

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Bibliografiske detaljer
Main Authors: Bignell, Graham R., Huang, Jing, Greshock, Joel, Watt, Stephen, Butler, Adam, West, Sofie, Grigorova, Mira, Jones, Keith W., Wei, Wen, Stratton, Michael R., Futreal, P. Andrew, Weber, Barbara, Shapero, Michael H., Wooster, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC327104/
https://ncbi.nlm.nih.gov/pubmed/14762065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2012304
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