High-Resolution Analysis of DNA Copy Number Using Oligonucleotide Microarrays

Genomic copy number alterations are a feature of many human diseases including cancer. We have evaluated the effectiveness of an oligonucleotide array, originally designed to detect single-nucleotide polymorphisms, to assess DNA copy number. We first showed that fluorescent signal from the oligonucl...

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Main Authors: Bignell, Graham R., Huang, Jing, Greshock, Joel, Watt, Stephen, Butler, Adam, West, Sofie, Grigorova, Mira, Jones, Keith W., Wei, Wen, Stratton, Michael R., Futreal, P. Andrew, Weber, Barbara, Shapero, Michael H., Wooster, Richard
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2004
主題:
Methods
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC327104/
https://ncbi.nlm.nih.gov/pubmed/14762065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2012304
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