High-Resolution Analysis of DNA Copy Number Using Oligonucleotide Microarrays

Genomic copy number alterations are a feature of many human diseases including cancer. We have evaluated the effectiveness of an oligonucleotide array, originally designed to detect single-nucleotide polymorphisms, to assess DNA copy number. We first showed that fluorescent signal from the oligonucl...

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Autori principali: Bignell, Graham R., Huang, Jing, Greshock, Joel, Watt, Stephen, Butler, Adam, West, Sofie, Grigorova, Mira, Jones, Keith W., Wei, Wen, Stratton, Michael R., Futreal, P. Andrew, Weber, Barbara, Shapero, Michael H., Wooster, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
Soggetti:
Methods
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC327104/
https://ncbi.nlm.nih.gov/pubmed/14762065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2012304
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