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The Bridge Helix of RNA Polymerase Acts as a Central Nanomechanical Switchboard for Coordinating Catalysis and Substrate Movement

The availability of in vitro assembly systems to produce recombinant archaeal RNA polymerases (RNAPs) offers one of the most powerful experimental tools for investigating the still relatively poorly understood molecular mechanisms underlying RNAP function. Over the last few years, we pioneered new r...

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Autore principale: Weinzierl, Robert O. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270539/
https://ncbi.nlm.nih.gov/pubmed/22312317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/608385
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