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Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice
Here we investigate the regulation of hepcidin, a hormone that inhibits dietary iron absorption and macrophage iron recycling, by the serum iron-binding protein transferrin. Mice deficient in transferrin (Tf(hpx/hpx)) and hemojuvelin (Hjv(−/−)), a gene mutated in juvenile hemochromatosis, a disease...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ferrata Storti Foundation
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269476/ https://ncbi.nlm.nih.gov/pubmed/21993681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.054031 |
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