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Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

As a central regulator of iron metabolism, hepcidin inhibits dietary iron absorption and macrophage iron recycling. Its expression is regulated by multiple factors including iron availability and erythropoietic activity. To investigate the role of transferrin (Tf) in the regulation of hepcidin expre...

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Main Authors: Bartnikas, Thomas B., Andrews, Nancy C., Fleming, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031485/
https://ncbi.nlm.nih.gov/pubmed/20956801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-287359
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