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Polymer supported synthesis of oligonucleotides by a phosphotriester method
A new polymer supported synthesis of deoxyribooligonucleotides which can be adapted to automation is described. The method is based on the elongation of an oligomer chain in the 5′- to 3′ -end direction using the modified phosphotriester chemistry. The approach is exemplified by the synthesis of a n...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1982
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC326919/ https://ncbi.nlm.nih.gov/pubmed/7177849 |
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