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Silica gel: an improved support for the solid-phase phosphotriester synthesis of oligonucleotides.

The phosphotriester method for the stepwise synthesis of deoxyoligonucleotides has been employed using HPLC-grade silica gel (Porasil B) as the solid support. The procedure results in a convenient flow-through system for the synthesis of oligomers where all the reaction steps including the zinc brom...

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Main Authors: Kohli, V, Balland, A, Wintzerith, M, Sauerwald, R, Staub, A, Lecocq, J P
格式: Artigo
語言:Inglês
出版: 1982
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC327016/
https://ncbi.nlm.nih.gov/pubmed/6296777
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