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Polymer supported synthesis of oligonucleotides by a phosphotriester method

A new polymer supported synthesis of deoxyribooligonucleotides which can be adapted to automation is described. The method is based on the elongation of an oligomer chain in the 5′- to 3′ -end direction using the modified phosphotriester chemistry. The approach is exemplified by the synthesis of a n...

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Main Authors: Belagaje, Ramamoorthy, Brush, Charles K.
格式: Artigo
語言:Inglês
出版: 1982
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC326919/
https://ncbi.nlm.nih.gov/pubmed/7177849
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