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Sirtuins and Disease: The Road Ahead
Sirtuins represent a promising new class of conserved histone deacetylases, originally identified in yeast. The activity of the sirtuin (SirT) family – made up of seven members (SirT1-7) – is NAD(+) dependent. Sirtuins target a wide range of cellular proteins in nucleus, cytoplasm, and mitochondria...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Research Foundation
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269041/ https://ncbi.nlm.nih.gov/pubmed/22319497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00004 |
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