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Nucleic acid-free mutation of prion strains

While prions share the ability to propagate strain information with nucleic acid-based pathogens, it is unclear how they mutate and acquire fitness in the absence of this informational component. Because prion diseases occur as epidemics, understanding this mechanism is of paramount importance for i...

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Detalles Bibliográficos
Autor Principal: Telling, Glenn C
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268957/
https://ncbi.nlm.nih.gov/pubmed/20948302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.4.4.13675
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