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Nucleic acid-free mutation of prion strains
While prions share the ability to propagate strain information with nucleic acid-based pathogens, it is unclear how they mutate and acquire fitness in the absence of this informational component. Because prion diseases occur as epidemics, understanding this mechanism is of paramount importance for i...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268957/ https://ncbi.nlm.nih.gov/pubmed/20948302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.4.4.13675 |
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