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Taxol alleviates 2-methoxyestradiol-induced endothelial permeability
We have previously shown that the anti-cancer agent 2-methoxyestradiol (2ME) induces hyperpermeability across endothelial monolayers. Here, we show that both microtubule disruptor, 2ME, and microtubule stabilizer, paclitaxel (taxol), increase vascular lung permeability in vitro and in vivo. Simultan...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268947/ https://ncbi.nlm.nih.gov/pubmed/22074808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2011.10.002 |
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