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Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability

Up to date, the nature of the sepsis-induced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we studied the protective effect of cAMP using endotoxin-induced hyperpermeability as a model for barrier dysfunction observed in gram-negative...

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Bibliografiske detaljer
Main Authors: Bogatcheva, Natalia V., Zemskova, Marina A., Kovalenkov, Yevgeniy, Poirier, Christophe, Verin, Alexander D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758045/
https://ncbi.nlm.nih.gov/pubmed/19725051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21913
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