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The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?

Sepsis-induced vascular leakage is a major underlying cause of the respiratory dysfunction seen in severe sepsis. Here we studied the role of MLC phosphorylation in LPS-induced endothelial hyperpermeability and assessed how the changes in phospho-MLC distribution affect LPS-induced barrier dysfuncti...

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Detalhes bibliográficos
Main Authors: Bogatcheva, Natalia V., Zemskova, Marina A., Poirier, Christophe, Mirzapoiazova, Tamara, Kolosova, Irina, Bresnick, Anne R., Verin, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130083/
https://ncbi.nlm.nih.gov/pubmed/21302311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22669
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