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KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma

Distinctive histological variants of lung cancer are increasingly recognized to have specific genetic changes that impact tumor biology and response to therapy. In this study, we evaluated true papillary adenocarcinoma of the lung, proposed as a distinct diagnostic category with relatively poor resp...

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Detalhes bibliográficos
Main Authors: Li, Qing Kay, Singh, Anju, Biswal, Shyam, Askin, Frederic, Gabrielson, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268659/
https://ncbi.nlm.nih.gov/pubmed/21248763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2010.172
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