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Deletion of Keap1 in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation

Exposure to cigarette smoke (CS) is the primary factor associated with the development of chronic obstructive pulmonary disease (COPD). CS increases the level of oxidants in the lungs, resulting in a depletion of antioxidants, which promotes oxidative stress and the destruction of alveolar tissue. I...

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Detalhes bibliográficos
Main Authors: Blake, David J., Singh, Anju, Kombairaju, Ponvijay, Malhotra, Deepti, Mariani, Thomas J., Tuder, Rubin M., Gabrielson, Edward, Biswal, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874439/
https://ncbi.nlm.nih.gov/pubmed/19520915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0054OC
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