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Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer
BACKGROUND: Nuclear factor erythroid-2 related factor 2 (NRF2) is a redox-sensitive transcription factor that positively regulates the expression of genes encoding antioxidants, xenobiotic detoxification enzymes, and drug efflux pumps, and confers cytoprotection against oxidative stress and xenobiot...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1584412/ https://ncbi.nlm.nih.gov/pubmed/17020408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030420 |
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