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Transcription Factor NF-κB Regulates Expression of Pore-forming Ca(2+) Channel Unit, Orai1, and Its Activator, STIM1, to Control Ca(2+) Entry and Affect Cellular Functions
The serum and glucocorticoid-inducible kinase SGK1 increases the activity of Orai1, the pore forming unit of store-operated Ca(2+) entry, and thus influences Ca(2+)-dependent cellular functions such as migration. SGK1 further regulates transcription factor nuclear factor κB (NF-κB). This study explo...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268429/ https://ncbi.nlm.nih.gov/pubmed/22110130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275925 |
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