Stimulation of Ca(2+)-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1)

Ca(2+) signaling includes store-operated Ca(2+) entry (SOCE) following depletion of endoplasmic reticulum (ER) Ca(2+) stores. On store depletion, the ER Ca(2+) sensor STIM1 activates Orai1, the pore-forming unit of Ca(2+)-release-activated Ca(2+) (CRAC) channels. Here, we show that Orai1 is regulate...

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Main Authors: Eylenstein, Anja, Gehring, Eva-Maria, Heise, Nicole, Shumilina, Ekaterina, Schmidt, Sebastian, Szteyn, Kalina, Münzer, Patrick, Nurbaeva, Meerim K., Eichenmüller, Melanie, Tyan, Leonid, Regel, Ivonne, Föller, Michael, Kuhl, Dietmar, Soboloff, Jonathan, Penner, Reinhold, Lang, Florian
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2011
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999400/
https://ncbi.nlm.nih.gov/pubmed/21385992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-178210
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