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Stimulation of Ca(2+)-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1)
Ca(2+) signaling includes store-operated Ca(2+) entry (SOCE) following depletion of endoplasmic reticulum (ER) Ca(2+) stores. On store depletion, the ER Ca(2+) sensor STIM1 activates Orai1, the pore-forming unit of Ca(2+)-release-activated Ca(2+) (CRAC) channels. Here, we show that Orai1 is regulate...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999400/ https://ncbi.nlm.nih.gov/pubmed/21385992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-178210 |
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