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Strandwise translocation of a DNA glycosylase on undamaged DNA

Base excision repair of genotoxic nucleobase lesions in the genome is critically dependent upon the ability of DNA glycosylases to locate rare sites of damage embedded in a vast excess of undamaged DNA, using only thermal energy to fuel the search process. Considerable interest surrounds the questio...

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Hlavní autoři: Qi, Yan, Nam, Kwangho, Spong, Marie C., Banerjee, Anirban, Sung, Rou-Jia, Zhang, Michael, Karplus, Martin, Verdine, Gregory L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268267/
https://ncbi.nlm.nih.gov/pubmed/22219368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111237108
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