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An approach to crystallizing proteins by metal-mediated synthetic symmetrization
Combining the concepts of synthetic symmetrization with the approach of engineering metal-binding sites, we have developed a new crystallization methodology termed metal-mediated synthetic symmetrization. In this method, pairs of histidine or cysteine mutations are introduced on the surface of targe...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267952/ https://ncbi.nlm.nih.gov/pubmed/21898649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.727 |
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