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An approach to crystallizing proteins by synthetic symmetrization

Previous studies of symmetry preferences in protein crystals suggest that symmetric proteins, such as homodimers, might crystallize more readily on average than asymmetric, monomeric proteins. Proteins that are naturally monomeric can be made homodimeric artificially by forming disulfide bonds betwe...

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Detalhes bibliográficos
Main Authors: Banatao, D. Rey, Cascio, Duilio, Crowley, Christopher S., Fleissner, Mark R., Tienson, Heather L., Yeates, Todd O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637565/
https://ncbi.nlm.nih.gov/pubmed/17050682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607674103
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