Activation of Wnt Signaling by Chemically Induced Dimerization of LRP5 Disrupts Cellular Homeostasis

Wnt signaling is crucial for a variety of biological processes, including body axis formation, planar polarity, stem cell maintenance and cellular differentiation. Therefore, targeted manipulation of Wnt signaling in vivo would be extremely useful. By applying chemical inducer of dimerization (CID)...

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Bibliografiske detaljer
Main Authors: Shahi, Payam, Park, Dongsu, Pond, Adam C., Seethammagari, Mamatha, Chiou, Shin-Heng, Cho, Kyucheol, Carstens, Julienne L., Decker, William K., McCrea, Pierre D., Ittmann, Michael M., Rosen, Jeffrey M., Spencer, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267738/
https://ncbi.nlm.nih.gov/pubmed/22303459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030814
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