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The E3 ligase c-Cbl regulates dendritic cell activation
The activation of innate and adaptive immunity is always balanced by inhibitory signalling mechanisms to maintain tissue integrity. We have identified the E3 ligase c-Cbl––known for its roles in regulating lymphocyte signalling––as a modulator of dendritic cell activation. In c-Cbl-deficient dendrit...
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Hoofdauteurs: | , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Nature Publishing Group
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166462/ https://ncbi.nlm.nih.gov/pubmed/21799517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.143 |
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