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A motif-independent metric for DNA sequence specificity

BACKGROUND: Genome-wide mapping of protein-DNA interactions has been widely used to investigate biological functions of the genome. An important question is to what extent such interactions are regulated at the DNA sequence level. However, current investigation is hampered by the lack of computation...

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Bibliografiske detaljer
Main Authors: Pinello, Luca, Lo Bosco, Giosuè, Hanlon, Bret, Yuan, Guo-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267244/
https://ncbi.nlm.nih.gov/pubmed/22017798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-408
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