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A motif-independent metric for DNA sequence specificity

BACKGROUND: Genome-wide mapping of protein-DNA interactions has been widely used to investigate biological functions of the genome. An important question is to what extent such interactions are regulated at the DNA sequence level. However, current investigation is hampered by the lack of computation...

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Detalhes bibliográficos
Main Authors: Pinello, Luca, Lo Bosco, Giosuè, Hanlon, Bret, Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267244/
https://ncbi.nlm.nih.gov/pubmed/22017798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-408
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