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A motif-independent metric for DNA sequence specificity

BACKGROUND: Genome-wide mapping of protein-DNA interactions has been widely used to investigate biological functions of the genome. An important question is to what extent such interactions are regulated at the DNA sequence level. However, current investigation is hampered by the lack of computation...

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Autors principals: Pinello, Luca, Lo Bosco, Giosuè, Hanlon, Bret, Yuan, Guo-Cheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267244/
https://ncbi.nlm.nih.gov/pubmed/22017798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-408
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