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Neck-motor interactions trigger rotation of the kinesin stalk

Rotation of the coiled-coil stalk of the kinesin-14 motors is thought to drive displacements or steps by the motor along microtubules, but the structural changes that trigger stalk rotation and the nucleotide state in which it occurs are not certain. Here we report a kinesin-14 neck mutant that rele...

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Detalhes bibliográficos
Main Authors: Liu, Hong-Lei, Pemble IV, Charles W., Endow, Sharyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266953/
https://ncbi.nlm.nih.gov/pubmed/22355749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00236
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