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Neck-motor interactions trigger rotation of the kinesin stalk

Rotation of the coiled-coil stalk of the kinesin-14 motors is thought to drive displacements or steps by the motor along microtubules, but the structural changes that trigger stalk rotation and the nucleotide state in which it occurs are not certain. Here we report a kinesin-14 neck mutant that rele...

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Autori principali: Liu, Hong-Lei, Pemble IV, Charles W., Endow, Sharyn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266953/
https://ncbi.nlm.nih.gov/pubmed/22355749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00236
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