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Neck-motor interactions trigger rotation of the kinesin stalk

Rotation of the coiled-coil stalk of the kinesin-14 motors is thought to drive displacements or steps by the motor along microtubules, but the structural changes that trigger stalk rotation and the nucleotide state in which it occurs are not certain. Here we report a kinesin-14 neck mutant that rele...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hong-Lei, Pemble IV, Charles W., Endow, Sharyn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266953/
https://ncbi.nlm.nih.gov/pubmed/22355749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00236
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