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Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse
Normal development of the mammalian embryo requires epigenetic reprogramming of the genome. The level of cytosine methylation of CpG-rich (5meC) regions of the genome is a major epigenetic regulator and active global demethylation of 5meC throughout the genome is reported to occur within the first c...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266909/ https://ncbi.nlm.nih.gov/pubmed/22292019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030687 |
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