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Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse

Normal development of the mammalian embryo requires epigenetic reprogramming of the genome. The level of cytosine methylation of CpG-rich (5meC) regions of the genome is a major epigenetic regulator and active global demethylation of 5meC throughout the genome is reported to occur within the first c...

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Hlavní autoři: Li, Yan, O'Neill, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266909/
https://ncbi.nlm.nih.gov/pubmed/22292019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030687
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