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Mapping global changes in nuclear cytosine base modifications in the early mouse embryo
Reprogramming epigenetic modifications to cytosine is required for normal embryo development. We used improved immunolocalization techniques to simultaneously map global changes in the levels of 5′-methylcytosine (5meC) and 5′-hydroxymethylcytosine (5hmC) in each cell of the embryo from fertilizatio...
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| Publicado no: | Reproduction |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bioscientifica Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676261/ https://ncbi.nlm.nih.gov/pubmed/26660107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-15-0207 |
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