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Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

Organismal aging is influenced by a multitude of intrinsic and extrinsic factors, and heterochromatin loss has been proposed to be one of the causes of aging. However, the role of heterochromatin in animal aging has been controversial. Here we show that heterochromatin formation prolongs lifespan an...

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Bibliografiske detaljer
Main Authors: Larson, Kimberly, Yan, Shian-Jang, Tsurumi, Amy, Liu, Jacqueline, Zhou, Jun, Gaur, Kriti, Guo, Dongdong, Eickbush, Thomas H., Li, Willis X.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266895/
https://ncbi.nlm.nih.gov/pubmed/22291607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002473
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