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Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

Organismal aging is influenced by a multitude of intrinsic and extrinsic factors, and heterochromatin loss has been proposed to be one of the causes of aging. However, the role of heterochromatin in animal aging has been controversial. Here we show that heterochromatin formation prolongs lifespan an...

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Detalhes bibliográficos
Main Authors: Larson, Kimberly, Yan, Shian-Jang, Tsurumi, Amy, Liu, Jacqueline, Zhou, Jun, Gaur, Kriti, Guo, Dongdong, Eickbush, Thomas H., Li, Willis X.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266895/
https://ncbi.nlm.nih.gov/pubmed/22291607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002473
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