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Pivotal role of the CCL5/CCR5 interaction for recruitment of endothelial progenitor cells in mouse wound healing

BM-derived endothelial progenitor cells (EPCs) are critical and essential for neovascularization in tissue repair and tumorigenesis. EPCs migrate from BM to tissues via the bloodstream, but specific chemotactic cues have not been identified. Here we show in mice that the absence of CCR5 reduced vasc...

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Bibliografske podrobnosti
Main Authors: Ishida, Yuko, Kimura, Akihiko, Kuninaka, Yumi, Inui, Masanori, Matsushima, Kouji, Mukaida, Naofumi, Kondo, Toshikazu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266771/
https://ncbi.nlm.nih.gov/pubmed/22214846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43027
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