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The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

Lafora disease (LD), an inherited and fatal neurodegenerative disorder, is characterized by increased cellular glycogen content and the formation of abnormally branched glycogen inclusions, called Lafora bodies, in the affected tissues, including neurons. Therefore, laforin phosphatase and malin ubi...

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Detalhes bibliográficos
Main Authors: Singh, Pankaj Kumar, Singh, Sweta, Ganesh, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266598/
https://ncbi.nlm.nih.gov/pubmed/22124153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06353-11
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