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The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

Lafora disease (LD), an inherited and fatal neurodegenerative disorder, is characterized by increased cellular glycogen content and the formation of abnormally branched glycogen inclusions, called Lafora bodies, in the affected tissues, including neurons. Therefore, laforin phosphatase and malin ubi...

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Autori principali: Singh, Pankaj Kumar, Singh, Sweta, Ganesh, Subramaniam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266598/
https://ncbi.nlm.nih.gov/pubmed/22124153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06353-11
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