Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase

In Lafora disease (LD), deficiency of either EPM2A or NHLRC1, the genes encoding the phosphatase laforin and E3 ligase respectively, causes massive accumulation of less-branched glycogen inclusions, known as Lafora bodies, also called polyglucosan bodies (PBs), in several types of cells including ne...

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Bibliographic Details
Main Authors:	Liu, Yan, Zeng, Li, Ma, Keli, Baba, Otto, Zheng, Pen, Liu, Yang, Wang, Yin
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3954894/ https://ncbi.nlm.nih.gov/pubmed/24068615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8546-z
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Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase

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