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The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

Lafora disease (LD), an inherited and fatal neurodegenerative disorder, is characterized by increased cellular glycogen content and the formation of abnormally branched glycogen inclusions, called Lafora bodies, in the affected tissues, including neurons. Therefore, laforin phosphatase and malin ubi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Singh, Pankaj Kumar, Singh, Sweta, Ganesh, Subramaniam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266598/
https://ncbi.nlm.nih.gov/pubmed/22124153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06353-11
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