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DELETION OF G PROTEIN-COUPLED ESTROGEN RECEPTOR INCREASES ENDOTHELIAL VASOCONSTRICTION

Endogenous estrogens mediate protective effects in the cardiovascular system, affecting both endothelium-dependent and -independent mechanisms. Previous studies have suggested that nonselective estrogen receptor agonists such as endogenous estrogens inhibit endothelium-dependent vasoconstriction; ho...

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Bibliographic Details
Main Authors: Meyer, Matthias R., Amann, Kerstin, Field, Angela S., Hu, Chelin, Hathaway, Helen J., Kanagy, Nancy L., Walker, Mary K., Barton, Matthias, Prossnitz, Eric R.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266468/
https://ncbi.nlm.nih.gov/pubmed/22203741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184606
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