Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice

This study investigated the mechanisms underlying tubular apoptosis in diabetes by identifying proapoptotic genes that are differentially upregulated by reactive oxygen species in renal proximal tubular cells (RPTCs) in models of diabetes. Total RNAs isolated from renal proximal tubules (RPTs) of 20...

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Autors principals: Lau, Garnet J., Godin, Nicolas, Maachi, Hasna, Lo, Chao-Sheng, Wu, Shyh-Jong, Zhu, Jian-Xin, Brezniceanu, Marie-Luise, Chénier, Isabelle, Fragasso-Marquis, Joelle, Lattouf, Jean-Baptiste, Ethier, Jean, Filep, Janos G., Ingelfinger, Julie R., Nair, Viji, Kretzler, Matthias, Cohen, Clemens D., Zhang, Shao-Ling, Chan, John S.D.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Complications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266424/
https://ncbi.nlm.nih.gov/pubmed/22210314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0141
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