FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest

Mitotic progression is regulated by ubiquitin E3 ligase complexes to carefully orchestrate eukaryotic cell division. Here, we show that a relatively new E3 ligase component belonging to the SCF (Skip-Cullin1-F-box protein) E3 ligase family, SCF(FBXL2), impairs cell proliferation by mediating cyclin...

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Bibliographic Details
Main Authors: Chen, Bill B, Glasser, Jennifer R, Coon, Tiffany A, Mallampalli, Rama K
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266178/
https://ncbi.nlm.nih.gov/pubmed/22024926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.20.17742
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