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Mechanistic study of E. coli DNA topoisomerase I: cleavage of oligonucleotides.

E. coli DNA topoisomerase I catalyzes DNA topoisomerization by transiently breaking and rejoining single DNA strands (1). When an enzyme-DNA incubation mixture is treated with alkaline or detergent, DNA strand cleavage occurs, and the enzyme becomes covalently linked to the 5'-phosphoryl end of...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tse-Dinh, Y C, McCarron, B G, Arentzen, R, Chowdhry, V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1983
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC326617/
https://ncbi.nlm.nih.gov/pubmed/6324095
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