Common Polymorphisms in the PKP3-SIGIRR-TMEM16J Gene Region Are Associated With Susceptibility to Tuberculosis

(See the editorial commentary by Wilkinson, on pages 525–7.) Background. Tuberculosis has been associated with genetic variation in host immunity. We hypothesized that single-nucleotide polymorphisms (SNPs) in SIGIRR, a negative regulator of Toll-like receptor/IL-1R signaling, are associated with su...

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Autors principals: Horne, David J., Randhawa, April K., Chau, Tran T. H., Bang, Nguyen D., Yen, Nguyen T. B., Farrar, Jeremy J., Dunstan, Sarah J., Hawn, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266131/
https://ncbi.nlm.nih.gov/pubmed/22223854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir785
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