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Common Polymorphisms in the PKP3-SIGIRR-TMEM16J Gene Region Are Associated With Susceptibility to Tuberculosis

(See the editorial commentary by Wilkinson, on pages 525–7.) Background. Tuberculosis has been associated with genetic variation in host immunity. We hypothesized that single-nucleotide polymorphisms (SNPs) in SIGIRR, a negative regulator of Toll-like receptor/IL-1R signaling, are associated with su...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Horne, David J., Randhawa, April K., Chau, Tran T. H., Bang, Nguyen D., Yen, Nguyen T. B., Farrar, Jeremy J., Dunstan, Sarah J., Hawn, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266131/
https://ncbi.nlm.nih.gov/pubmed/22223854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir785
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