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Inhibition of Phosphorylation of Na(+),K(+)-ATPase by Mutations Causing Familial Hemiplegic Migraine

The neurological disorder familial hemiplegic migraine type II (FHM2) is caused by mutations in the α2-isoform of the Na(+),K(+)-ATPase. We have studied the partial reaction steps of the Na(+),K(+)-pump cycle in nine FHM2 mutants retaining overall activity at a level still compatible with cell growt...

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Detalhes bibliográficos
Main Authors: Schack, Vivien Rodacker, Holm, Rikke, Vilsen, Bente
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265897/
https://ncbi.nlm.nih.gov/pubmed/22117059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323022
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