Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 Integrin Mediates Interaction of Melanoma Cells with Platelets: A CONNECTION TO HEMATOGENOUS METASTASIS

A mutual relationship exists between metastasizing tumor cells and components of the coagulation cascade. The exact mechanisms as to how platelets influence blood-borne metastasis, however, remain poorly understood. Here, we used murine B16 melanoma cells to observe functional aspects of how platele...

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Bibliografske podrobnosti
Main Authors: Lonsdorf, Anke S., Krämer, Björn F., Fahrleitner, Manuela, Schönberger, Tanja, Gnerlich, Stephan, Ring, Sabine, Gehring, Sarah, Schneider, Stefan W., Kruhlak, Michael J., Meuth, Sven G., Nieswandt, Bernhard, Gawaz, Meinrad, Enk, Alexander H., Langer, Harald F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265895/
https://ncbi.nlm.nih.gov/pubmed/22102277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269811
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