Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 Integrin Mediates Interaction of Melanoma Cells with Platelets: A CONNECTION TO HEMATOGENOUS METASTASIS

A mutual relationship exists between metastasizing tumor cells and components of the coagulation cascade. The exact mechanisms as to how platelets influence blood-borne metastasis, however, remain poorly understood. Here, we used murine B16 melanoma cells to observe functional aspects of how platele...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lonsdorf, Anke S., Krämer, Björn F., Fahrleitner, Manuela, Schönberger, Tanja, Gnerlich, Stephan, Ring, Sabine, Gehring, Sarah, Schneider, Stefan W., Kruhlak, Michael J., Meuth, Sven G., Nieswandt, Bernhard, Gawaz, Meinrad, Enk, Alexander H., Langer, Harald F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265895/
https://ncbi.nlm.nih.gov/pubmed/22102277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269811
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