ロード中...

Fructose Protects Murine Hepatocytes from Tumor Necrosis Factor-induced Apoptosis by Modulating JNK Signaling

Fructose-induced hepatic ATP depletion prevents TNF-induced apoptosis, whereas it contrarily enhances CD95-induced hepatocyte apoptosis in vitro and in vivo. By contrast, transformed liver cells are not protected against TNF due to metabolic alterations, allowing selective tumor targeting. We analyz...

詳細記述

保存先:
書誌詳細
主要な著者: Speicher, Tobias, Köhler, Ulrike A., Choukèr, Alexander, Werner, Sabine, Weiland, Timo, Wendel, Albrecht
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265865/
https://ncbi.nlm.nih.gov/pubmed/22086922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266742
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!